Semaglutide
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What is Semaglutide?
Semaglutide is a FDA approved is an injectable glucagon-like peptide-1 (GLP-1) agonist that’s administered once weekly for obesity.
How does it work for weight loss?
GLP-1 is an incretin hormone that plays a role in your appetite and digestion. Incretins — hormones released by your small intestine — are sent out by your body after you’ve eaten a meal to help lower your blood sugar by triggering insulin and blocking other sources of sugar.
It also slows down how quickly food leaves your stomach (called gastric emptying). The result of these actions causes you to feel full — lowering your appetite and causing you to lose weight. Medications like GLP-1 agonists are referred to as incretin mimetics since they “mimic” these effects.
Potential Side Effects
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Potential Side Effects
Gastrointestinal (GI) side effects tend to happen most frequently when using this medication — the most common being nausea, constipation, and vomiting. You may experience these effects more strongly when your provider raises your dose. Additional common side effects can include stomach pain, indigestion and bloating.
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Nausea/Constipation
Nausea: Eat small, frequent meals .Lower the amount of alcohol you consume - eat low-fat meals (bland diet-bananas, rice, toast). Take ginger, Unisom, Vitamin B6 for nausea.
Constipation: Stay hydrated, continue with exercise. Eat a high-fiber dcet. Use anoover tnt counter stool softener.
Contraindications to treatment:
Personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN 2)
Pregnant or breastfeeding
If you are diabetic, please contact your physician/provider
Past suicidal ideation, suicide attempt, uncontrolled psychiatric disorders.
Allergies to GLP-1 medications
History of pancreatitis or severe alcohol consumption
Renal impairment
